Sample simulated data for exposure-response with continuous endpoint using linear model.

Usage

d_sim_lin

Format

A data frame with columns:

ID: Subject ID
AUCss: Steady-state area under the curve
Cmaxss: Steady-state maximum (peak) concentration
BAGE: Baseline age in years
SEX: M or F
response: Response

Details

True model is defined as 0.5 * AUCss + 0.5 * BAGE + 5 * SEX, with variability added with standard deviation of 10. You can find the data generating code in the package source code, under data-raw/d_sim_lin.R.

Examples

d_sim_lin
#> # A tibble: 101 × 6
#>       ID AUCss Cmaxss  BAGE SEX   response
#>    <int> <int>  <dbl> <dbl> <chr>    <dbl>
#>  1     1     0   0     45.3 F         37.8
#>  2     2     1   5.42  50.7 M         35.4
#>  3     3     2  13.3   45.0 F         36.7
#>  4     4     3   4.44  41.7 M         38.6
#>  5     5     4  22.6   51.7 F         35.2
#>  6     6     5  28.8   41.0 M         30.9
#>  7     7     6  24.8   51.7 F         20.3
#>  8     8     7  29.3   53.5 F         30.9
#>  9     9     8  33.2   49.5 F         26.9
#> 10    10     9  33.0   48.0 M         42.9
#> # ℹ 91 more rows