SIGnature#

Scoring the Importance of Genes using scRNA-seq Foundation Models#

SIGnature is a Python package that empowers researchers to rapidly query gene sets across diverse single-cell RNA sequencing (scRNA-seq) datasets through precomputed gene attribution scores.

Beyond querying capabilities, SIGnature also enables the generation of attribution scores on novel scRNA-seq data, allowing seamless integration with our collection of annotated studies.

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Capabilities#

Query Attributions#

signature.signature provides tools to query attributions across dozens of cell types from hundreds of studies.

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Generate attributions#

signature.signature also provides tools to generate attribution scores on new data that can be integrated with our collection of annotated datasets.

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Indices#