SIGnature ================================================================================ .. toctree:: :maxdepth: 1 :hidden: Overview Installation Tutorials API Reference Release Notes About Scoring the Importance of Genes using scRNA-seq Foundation Models -------------------------------------------------------------------------------- **SIGnature** is a Python package that empowers researchers to rapidly query gene sets across diverse single-cell RNA sequencing (scRNA-seq) datasets through precomputed gene attribution scores. Beyond querying capabilities, SIGnature also enables the generation of attribution scores on novel scRNA-seq data, allowing seamless integration with our collection of annotated studies. .. image:: _static/overview_image.png :width: 75% :align: center Capabilities -------------------------------------------------------------------------------- Query Attributions ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ :mod:`signature.signature` provides tools to query attributions across dozens of cell types from hundreds of studies. .. image:: _static/query_image.png :width: 75% :align: center Generate attributions ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ :mod:`signature.signature` also provides tools to generate attribution scores on new data that can be integrated with our collection of annotated datasets. .. image:: _static/generate_image.png :width: 75% :align: center Indices -------------------------------------------------------------------------------- | :ref:`genindex` | :ref:`modindex`