A matrix containing data from a clinical trial with a treatment arm and a control arm, as well as data from an external control. In this simulated dataset, the true hazard ratio (HR) for the time-to-event endpoint comparing the experimental treatment to the control treatment is 0.70. The true odds ratio (OR) for the binary response endpoint comparing the experimental treatment to the control treatment is 1.20.
Format
A data frame with 500 rows and 11 columns. The distributions of patients is: 50 internal control patients, 100 internal experimental patients, 350 external control patients.
- id
patient identifier
- ext
0/1, flag for external controls
- trt
0/1, flag for treatment arm
- cov1
0/1, baseline covariate
- cov2
0/1, baseline covariate
- cov3
0/1, baseline covariate
- cov4
0/1, baseline covariate
- time
numeric >0, survival time
- status
0/1, indicator for event status (1 = had event, 0 = did not have event)
- cnsr
0/1, censoring indicator (1 = was censored, 0 = was not censored)
. This value is 1 - status.
- resp
0/1, indicator for response outcome (1 = had a response, 0 = did not have a response)