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Simulate Longitudinal Data from a GSF Model

Usage

SimLongitudinalGSF(
  times = c(-100, -50, 0, 50, 100, 150, 250, 350, 450, 550)/365,
  sigma = 0.01,
  mu_s = log(c(0.6, 0.4)),
  mu_g = log(c(0.25, 0.35)),
  mu_b = log(60),
  mu_phi = qlogis(c(0.4, 0.6)),
  omega_b = 0.2,
  omega_s = 0.2,
  omega_g = 0.2,
  omega_phi = 0.2,
  link_dsld = 0,
  link_ttg = 0,
  link_identity = 0,
  link_growth = 0
)

Arguments

times

(numeric)
the times to generate observations at.

sigma

(number)
the variance of the longitudinal values.

mu_s

(numeric)
the mean shrinkage rates.

mu_g

(numeric)
the mean growth rates.

mu_b

(numeric)
the mean baseline values.

mu_phi

(numeric)
the mean proportion of cells affected by the treatment

omega_b

(number)
the baseline value standard deviation.

omega_s

(number)
the shrinkage rate standard deviation.

omega_g

(number)
the growth rate standard deviation.

omega_phi

(number)
for the standard deviation of the proportion of cells affected by the treatment omega_phi.

link_dsld

(number)
the link coefficient for the derivative contribution.

link_ttg

(number)
the link coefficient for the time-to-growth contribution.

link_identity

(number)
the link coefficient for the SLD Identity contribution.

link_growth

(number)
the link coefficient for the growth parameter contribution.

Slots

sigma

(numeric)
See arguments.

mu_s

(numeric)
See arguments.

mu_g

(numeric)
See arguments.

mu_b

(numeric)
See arguments.

mu_phi

(numeric)
See arguments.

omega_b

(numeric)
See arguments.

omega_s

(numeric)
See arguments.

omega_g

(numeric)
See arguments.

omega_phi

(numeric)
See arguments.

link_dsld

(numeric)
See arguments.

link_ttg

(numeric)
See arguments.

link_identity

(numeric)
See arguments.

link_growth

(numeric)
See arguments.