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Borrowing methods

Choose an estimator for external control borrowing

ec_ipw()
EC-IPW method constructor
ec_aipw()
EC-AIPW method
did_ec_ipw()
DID-EC-IPW method
did_ec_aipw()
DID-EC-AIPW method
did_ec_or()
DID-EC-OR method constructor
scm()
SCM method constructor

Analysis

Set up and run a single analysis

setup_analysis_primary()
Set up a primary analysis with external control borrowing
setup_analysis_OLE()
Set up an open-label extension (OLE) analysis
run_analysis()
Run an analysis with external control borrowing

Simulation

Evaluate operating characteristics via Monte Carlo

setup_simulation_primary()
Construct a simulation object for primary analysis
setup_simulation_OLE()
Construct a simulation object for OLE analysis
run_simulation()
Evaluate operating characteristics via Monte Carlo simulation

Data generation

Simulate trial and external control data

simulate_trial()
Simulate trials
simulate_X_copula()
Simulate covariates using a copula
simulate_X_dct_mvnorm()
Simulate covariates by discretizing a multivariate normal
simulate_X_mixture()
Simulate covariates from a Gaussian mixture model
simulate_trt_assign()
Simulate treatment assignment
simulate_trial_status()
Simulate trial participation status
simulate_outcome_from_model()
Simulate outcomes from additive linear models

Data

SyntheticData
Synthetic example dataset for rdborrow